How are plant chromosomes arranged? Is it possible to relate the genetic and cytological maps to an assembled genome sequence? Are there sequences present at centromeres that signal the cell to construct kinetochores, the machines that ensure proper chromosome segregation to occur, at the correct site?
As the genomes of more plants get sequenced, complex questions like these can can be translated into testable hypotheses. Eventually the content of plant genomes can be related to broad function, both within the cell and at the level of the organism as a whole.
Convergence of traditional biological investigation with genome content and organization is the focus of our work. We explore this area of research using maize, Arabidopsis, and other plants.